Wednesday, May 14, 2014

Cryoneedles A Possible Alternative To Botox In Fighting Against Wrinkles

Cryoneedles A Possible Alternative To Botox In Fighting Against Wrinkles.
A redone technology that while zaps away forehead wrinkles by freezing the nerves shows contract in early clinical trials, researchers say. The technique, if in the end approved by the US Food and Drug Administration, could provide an alternative to Botox and Dysport. Both are injectable forms of Botulinum toxin genus A, a neurotoxin that, when injected in mundane quantities, temporarily paralyzes facial muscles, thereby reducing wrinkles fav-store. "It's a toxin-free selection to treating unwanted lines and wrinkles, similar to what is being done with Botox and Dysport," said deliberate over co-author Francis Palmer, director of facial plastic surgery at the University of Southern California School of Medicine in Los Angeles.

And "From the at cock crow clinical trials, this procedure - which its maker calls cryoneuromodulation - appears to have the same clinical efficacy and protection comparable to the existing techniques". Palmer is also consulting medical executive of MyoScience Inc, the Redwood City (California) - based partnership developing the cryotechnology pill larder. The results of the clinical trials were to be presented Friday at an American Society for Laser Medicine and Surgery (ASLMS) symposium in Grapevine, Texas.

To do the procedure, physicians use stinting needles - "cryoprobes" - to deliver cold to nerves contest through the forehead, specifically the temporal branch of the frontal nerve, Palmer said. The icy freezes the nerve, which interrupts the nerve signal and relaxes the muscle that causes vertical and prone forehead lines. Although the nerve quickly returns to normal body temperature, the depressing temporarily "injures" the nerve, allowing the signal to remain interrupted for some period of time after the resolved leaves the office.

The technique does not permanently damage the nerve, Palmer said. Researchers said they are still refining the knowledge and could not say how long the effect lasts, but it seems to be comparable to Botox, which workings for about three to four months, Palmer said. Physicians would need training to identify the pluck that should be targeted, he added.

The 15-minute treatment is done using local anesthesia, according to the researchers. The current look at only looks at forehead wrinkles; future research will study the procedure elsewhere on the face, Palmer said. For the study, researchers tried the modus operandi on 31 people, all of whom had fewer wrinkles after two to eight injections. The most run-of-the-mill side effects were headaches and skin redness.

The storey of discomfort was comparable to that from Botox or fillers, Palmer said. But unlike Botox, which takes a few days to rebound in, the effects of the cryotechnology are seen immediately, the researchers say. Because this analysis was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

Palmer said he didn't sit down with the new technology as a replacement for Botox, but instead as an different for people who don't want an injection of a neurotoxin. The company will eventually seek FDA concurrence as a medical device. Palmer said the company might first seek approval in Europe.

Dr Brian Zelickson, an confederate professor of dermatology at the University of Minnesota in Minneapolis, said the technique sounds promising, but needs more inquiry to determine how long results last and to make sure no long-term nerve or muscle injury occurs that could cause permanent changes in sensation. He agreed that the toxin-free cosmetic policy might win some followers.

So "Botox and Dysport are very easy, very quick, the patient comfort profile is great and there are very few side effects," said Zelickson, incoming president of ASLMS. "It's a apex bar to leap over, but there are some people that don't like the concept of injecting Botulinum toxin into their bodies. If there were a tradition that could be done, that doesn't inject any chemical into the system and could yield the same results for the same duration, there is a exchange for that" carallumaburn.drug-purchase.info. According to the American Society for Aesthetic Plastic Surgery, Botox and Dysport injections crop their list of nonsurgical procedures.

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