Researchers Have Made A Big Step In Understanding The Treatment Of Ovarian Cancer

Researchers Have Made A Big Step In Understanding The Treatment Of Ovarian Cancer.
New arrangement about the ahead stages of ovarian cancer may principal to the development of a new screening test for the cancer, US researchers say support. In the study, scientists uncovered original tumors and precancerous lesions in inclusion cysts, which close into the ovary from its surface.

So "This is the first study giving very strong evidence that a substantial number of ovarian cancers mount in inclusion cysts and that there is indeed a precursor lesion that you can see, put your hands on, and give a celebrity to," lead author Jeff Boyd, chief scientific officer at Fox Chase Cancer Center in Philadelphia, said in a front-page news release check out your url. "Ovarian cancer most of the take seems to arise in simple inclusion cysts of the ovary, as opposed to the surface epithelium".

Boyd and his colleagues analyzed ovaries removed from women with BRCA gene mutations (who have a 40 percent lifetime danger of developing ovarian cancer) and from women with no known genetic imperil factors for ovarian cancer. In both groups of women, gene utterance patterns in the cells of involvement cysts were dramatically different than normal ovarian surface cells.

For example, the cells of incorporation cysts had increased expression of genes that control cell division and chromosome movement. The researchers also found that cells from very dawn tumors and tumor precursor lesions frequently had extra chromosomes.

So "Previous studies only looked at this at the morphologic level, looking at a essay of tissue under a microscope. We did that but we also dissected away cells from general ovaries and early-stage cancers, and did genetic analyses. We showed that you could follow extending from normal cells to the precursor lesion, which we call dysplasia, to the actual cancer, and see them adjacent to one another within an numbering cyst".