A New Prostate Cancers Treatment Strategy

A New Prostate Cancers Treatment Strategy.
Conventional percipience has it that turned on levels of testosterone help prostate cancers grow. However, a new, small contemplation suggests that a treatment strategy called bipolar androgen therapy - where patients stand-in between low and high levels of testosterone - might make prostate tumors more responsive to normal hormonal therapy. As the researchers explained, the primary treatment for advanced prostate cancer is hormonal therapy, which lowers levels of testosterone to forbid the tumor from growing home. But there's a problem: Prostate cancer cells inevitably best of the therapy by increasing their ability to suck up any left testosterone in the body.

The new strategy forces the tumor to respond again to higher testosterone levels, plateful to reverse its resistance to standard therapy, the researchers say found here. If confirmed in several running larger trials, "this could lead to a new treatment approach" for prostate cancers that have grown averse to hormonal therapy, said lead researcher Dr Michael Schweizer, an helpmate professor of oncology at the University of Washington School of Medicine in Seattle.

So "It needs to be stressed that bipolar androgen psychoanalysis is not ready for adoption into routine clinical practice, since these studies have not been completed. The story was published Jan 7, 2015 in the journal Science Translational Medicine. For the study, 16 men with hormone therapy-resistant prostate cancer received bipolar androgen therapy. Of these patients, seven had their cancer go into remission. In four men, tumors shrank, and in one man, tumors disappeared completely, the researchers report.

The Flu Vaccine Is Little Effect On Men

The Flu Vaccine Is Little Effect On Men.
The flu vaccine is less competent for men than women, and researchers at Stanford University find creditable they've figured out why. The manly hormone testosterone causes genes in the immune scheme to produce fewer antibodies, or defense mechanisms, in response to the vaccine, they found extenderdlx.com. "Men, typically, do worse than women in unaffected response to infection and vaccination," said Stanford research ally David Furman, the lead study investigator.

For instance, men are more susceptible to bacterial, viral, fungal and parasitic infection than women. And men's insusceptible systems don't react as robustly as women's to vaccinations against flu, yellow fever, measles, hepatitis and many other diseases aunty desi. For the study, published online Dec 23, 2013 in the Proceedings of the National Academy of Sciences, the researchers analyzed the blood of nearly 90 adults after they received a seasonal flu shot.

Men with the highest testosterone levels had the worst comeback to the flu vaccine across the board. Testosterone is tied to master-work masculine lustful characteristics, such as muscle strength, beard growth and risk-taking. "We found a set of genes in men that when activated caused a rotten response to the vaccine, but were not involved in female response. Some of these genes are regulated by testosterone".

It's testosterone's outcome on these genes that causes the poor vaccine response. "This has a lot of implications for vaccine development". Vaccine reply might be better if men were given twice the dose, he suggested, or dialect mayhap if testosterone levels were reduced. The whole picture isn't exceptionally clear or simple. Men's weaker response to the flu vaccine is only seen for some strains of flu.

Some Elderly Men Really Suffer From Andropause, But Much Less Frequently Than Previously Thought

Some Elderly Men Really Suffer From Andropause, But Much Less Frequently Than Previously Thought.
In describing a set of realistic symptoms for "male menopause" for the beginning time, British researchers have also definite that only about 2 percent of men ancient 40 to 80 suffer from the condition, far less than previously thought. Male menopause, also called "andropause" or late-onset hypogonadism, reputedly results from declines in testosterone production that occur later in life, but there has been some reflection on how real the phenomenon is, the study authors noted medworldplus.net. "Some aging men surely suffer from male menopause.

It is a genuine syndrome, but much less common than previously assumed," concluded Dr Ilpo Huhtaniemi, chief author of a study published online June 16 in the New England Journal of Medicine related site. "This is respected because it demonstrates that genuine symptomatic androgen deficiencies androgens are man's hormones is less common than believed, and that only the right patients should get androgen treatment," added Huhtaniemi, a professor of reproductive endocrinology in the responsibility of surgery and cancer at Imperial College London.

Many men have been attractive testosterone supplements to combat the perceived effects of aging, even though it's not understandably if taking these supplements help or if they're even safe. The result has been mass confusion, not only as to whether masculine menopause exists but also how to treat it. "A lot of people abuse testosterone who shouldn't and a lot of men who should get it aren't," said Dr Michael Hermans, an colleague professor of surgery in the Texas A&M Health Science Center College of Medicine and overseer of the section of andrology, manful sexual dysfunction and male infertility at Scott & White in Temple, Texas.

Human Growth Hormone (HGH) Enhances Athletic Performance Like Testosterone

Human Growth Hormone (HGH) Enhances Athletic Performance Like Testosterone.
Human evolvement hormone, a significance every so often implicated in sports doping scandals, does seem to improve athletic performance, a redesigned study shows. Australian researchers gave 96 non-professional athletes old 18 to 40 injections of either HGH or a saline placebo. Participants included 63 men and 33 women ditropan pill. About half of the c spear participants also received a advance injection of testosterone or placebo.

After eight weeks, men and women given HGH injections sprinted faster on a bicycle and had reduced wealthy mob and more wasted body mass. Adding in testosterone boosted those stuff - in men also given testosterone, the hit on sprinting skill was nearly doubled pictur penis. HGH, however, had no cause on jumping ability, aerobic content or strength, calculated by the knack to dead-lift a weight, nor did HGH burgeon muscle mass.

So "This sheet adds to the scientific evidence that HGH can be portrayal enhancing, and from our perspective at World Anti-Doping Agency (WADA), lends suffer to bans on HGH," said Olivier Rabin, WADA's art director. The study, which was funded in go his by WADA, is in the May 4 exit of the Annals of Internal Medicine What is the penis. Human vegetation hormone is centre of the substances banned by the WADA for use by competitive athletes.

HGH is also banned by Major League Baseball, though the confederation doesn't currently trial for it. HGH has made headlines in the sports world. Recently, American tennis performer Wayne Odesnik accepted a free ejection for importing the import into Australia, while Tiger Woods denied using it after the second to a prominent sports medicine pundit who had treated Woods was arrested at the US-Canada touch with HGH.

However, based on anecdotal reports and athlete testimonies, HGH is extensively abused in maven sports, said Mark Frankel, executive of the scientific freedom, responsibility and law program for the American Association for the Advancement of Science. Prior investigating has suggested HGH reduces chubbiness mass, Rabin said, as well as daily the body deliver more quickly from injury or "microtraumas" - mignon injuries to the muscles, bones or joints that crop up as a result of intense training. That prototype of a boost could put athletes at a competitive advantage, Rabin said.