Some Antiepileptic Drugs During Pregnancy Can Have A Negative Impact On The Development Of The CNS Of The Teens

Some Antiepileptic Drugs During Pregnancy Can Have A Negative Impact On The Development Of The CNS Of The Teens.
Teens born to women who took two or more epilepsy drugs while fecund fared worse in set than peers with no prenatal aspect to those medications, a massive Swedish study has found. Also, teens born to epileptic mothers in non-exclusive tended to score lower in several subjects, including math and English large girth cocks. The findings be supportive earlier research that linked prenatal airing to epilepsy drugs, particularly valproic acid (brand names include Depakene and Depakote), to disputing effects on a child's ability to process information, solve problems and make decisions.

And "Our results suggest that view to several anti-epileptic drugs in utero may have a negative effect on a child's neurodevelopment," said inspect author Dr Lisa Forsberg of Karolinska University Hospital sildenafilrx. The over was published online Nov 4, 2010 in Epilepsia.

The study was retrospective, import that it looked backwards in time. Using national medical records and a study conducted by a specific hospital, Forsberg and her team identified women with epilepsy who gave birth between 1973 and 1986, as well as those who employed anti-epileptic drugs during pregnancy. The team then obtained records of children's school bringing off from a registry that provides grades for all students leaving school at 16, the age that mandatory instruction ends in Sweden.

The researchers identified 1,235 children born to epileptic mothers. Of those, 641 children were exposed to one anti-epileptic medicine and 429 to two or more; 165 children had no known unveiling to the medications. The researchers then compared those children's school exhibition to that of all other children born in Sweden (more than 1,3 million) during that 13-year period.

The teens exposed to more than one anti-epileptic treat in the womb were less likely to get a final grade than those in the general population, said Forsberg. Not receiving a absolute grade generally means not attending general school because of mental deficits.