The Same Gene Is Associated With Obesity And Dementia

The Same Gene Is Associated With Obesity And Dementia.
A variation of the obesity-related gene FTO may flourish the risk of Alzheimer's disease and dementia, finds a further Swedish study. Previous research has shown that the FTO gene affects body quantity index (BMI), levels of leptin (a hormone involved in appetite and metabolism), and the endanger for diabetes medworldplus. All vascular risk factors that have also been linked with the risk of Alzheimer's disease.

This unusual study, conducted by the Karolinska Institute in Stockholm, included more than 1000 Swedish people, age-old 75 and older, who were followed for nine years how big is arabian penis. They all underwent genetic testing at the start of the study.

Participants who carried an AA gene deviating in the FTO gene had a 58 percent increased peril of developing Alzheimer's and a 48 percent increased risk for dementia, compared to those without the variant. The researchers also said the hazard could be 100 percent higher for a person with the FTO-AA variant and a gene change called APOE4, which is the highest-risk variant of the known Alzheimer's-related gene called APOE.

So "One of the intriguing aspects of the results is that the increased gamble was independent of the traits previously associated with FTO, such as chubbiness and diabetes measured at baseline," wrote Dr Caroline Graff and colleagues at the Karolinska Institute, in a bulletin release. "Our results suggest that the mechanism by which FTO is associated with an increased jeopardize for Alzheimer's and dementia may be different from how it increases the risk for obesity".

The study was slated to be presented July 12 at the Alzheimer's Association International Conference on Alzheimer's Disease. "This is a fascinating first finding, which fits with the known connections between bravery health and brain health," Maria Carrillo, older director of medical and scientific relations at the Alzheimer's Association, said in an linking news release how can you tell if lose muscle. "However, we do need to see these results confirmed by other researchers".