Treatment Of Diabetes Is Different For Men And Women.
Widely second-hand diabetes drugs have sundry effects on men's and women's hearts, a remodelled study suggests. Researchers examined how three commonly prescribed treatments for type 2 diabetes artificial 78 patients who were divided into three groups. One group took metformin alone, the go along with group took metformin plus rosiglitazone (sold under the maker name Avandia) and the third group took metformin plus Lovaza, a type of fish oil tramadol. Metformin reduces blood sugar effort by the liver and improves insulin sensitivity.
Rosiglitazone also improves insulin tender-heartedness and moves free fatty acids out of the blood. Lovaza lowers blood levels of another pattern of fat called triglycerides. The researchers found that the drugs had very various and sometimes opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders cheapest vimax detox in newton. The investigate appears in the December issue of the American Journal of Physiology - Heart and Circulatory Physiology.
Although metformin had assertive heart effects in women, it caused the tenderness metabolism of men to burn less sugar and more fats. Chronic burning of fat by the courage results in harmful changes that can lead to heart failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making middle metabolism more normal in men, metformin solitary made it worse, looking even more like a diabetic heart," study major author Dr Robert Gropler said in a university news release.
And "But in women, metformin had the desired capacity - lowering fat metabolism and increasing glucose insight by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to reduce some of the negative heart slang shit of metformin alone in men. Taking rosiglitazone in addition to metformin further improved women's bravery metabolism, compared to taking metformin alone.
The addition of Lovaza to metformin did not have a strong effect either scheme for men or women, the researchers said. "Our study suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The memorize did not, however, test a cause-and-effect link between the drug combinations and consideration changes male enhancement cream india. It showed only an association.
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