Dysfunction Of The Autonomic Nervous System May Be A Marker Of Later Development Of Certain Types Of Kidney Disease

Dysfunction Of The Autonomic Nervous System May Be A Marker Of Later Development Of Certain Types Of Kidney Disease.
A person's stomach blend may advance insight into their future kidney health, a budding study suggests duramale. A high resting heart rate and low beat-to-beat affection rate variability were noted in study patients with an increased risk for kidney disease, according to a make public released online July 8 in advance of publication in an upcoming print issue of the Journal of the American Society of Nephrology.

The determination suggests that dysfunction of the autonomic nervous system - which regulates unconscious body functions such as heart rate, blood pressure, temperature and stress reaction - may be a marker for late development of certain types of kidney disease, explained Dr Daniel Brotman of Johns Hopkins University School of Medicine and colleagues, in a story liberation from the American Society of Nephrology enlargement. Previous studies have suggested a link between autonomic nervous group dysfunction (dysautonomia) and chronic kidney disease and its progression.

Brotman's team analyzed heart and kidney observations from 13241 US adults, aged 45 to 64, enrolled in a long-term inquiry of atherosclerosis risk. In general, a low resting heart rate and greater beat-to-beat variability in pith rate indicate a healthy autonomic nervous system and good cardiovascular health.

The researchers found that race with a high resting heart rate had a twofold increased danger of developing kidney failure years later, and those with a lower beat-to-beat variability in heart clip had a 1,5-times increased risk. Brotman and colleagues noted that this does not prove a cause-and-effect relationship, but they speculated that problems in the autonomic in a dither system may damage blood vessels in and around the kidneys.

So "We wait our findings will encourage further research to better define the putative role of the autonomic nervous system in precipitating and exacerbating renal kidney disability in humans," the authors wrote continue reading. "This, in turn, may at the end of the day lead to novel therapeutic approaches once the mechanisms for our findings are better characterized".