Risk Factors For Alzheimer's Disease.
Older adults with honour problems and a experience of concussion have more buildup of Alzheimer's disease-associated plaques in the brain than those who also had concussions but don't have tribute problems, according to a new study. "What we think it suggests is, head trauma is associated with Alzheimer's-type dementia - it's a jeopardize factor," said study researcher Michelle Mielke, an associate professor of epidemiology and neurology at Mayo Clinic Rochester. But it doesn't augur someone with head trauma is automatically going to develop Alzheimer's rang saaf karne or dagh dhabe door karne. Her over is published online Dec 26, 2013 and in the Jan 7, 2014 print emanate of the journal Neurology.

Previous studies looking at whether head trauma is a risk factor for Alzheimer's have come up with conflicting results, she noted. And Mielke stressed that she has found only a constituent or association, not a cause-and-effect relationship kronic herbal smoke japan. In the study, Mielke and her tandem evaluated 448 residents of Olmsted County, Minn, who had no signs of remembrance problems.

They also evaluated another 141 residents with memory and thinking problems known as calm cognitive impairment. More than 5 million Americans have Alzheimer's disease, according to the Alzheimer's Association. Plaques are deposits of a protein sliver known as beta-amyloid that can build up in between the brain's nerve cells. While most hoi polloi develop some with age, those who develop Alzheimer's generally get many more, according to the Alzheimer's Association.

They also wait on to get them in a predictable pattern, starting in brain areas crucial for memory. In the Mayo study, all participants were elderly 70 or older. The participants reported if they ever had a brain damage that involved loss of consciousness or memory. Of the 448 without any memory problems, 17 percent had reported a wisdom injury. Of the 141 with memory problems, 18 percent did.

This suggests that the connector between head trauma and the plaques is complex, Mielke said, as the proportion of subjects reporting concussion was the same in both groups. Brain scans were done on all the participants. Those who had both concussion history and cognitive deranged impairment had levels of amyloid plaques that were 18 percent higher than those with cognitive flaw but no head trauma history, the investigators found.

Among those with mild cognitive impairment, those with concussion histories had a nearly five times higher jeopardy of elevated plaque levels than those without a history of concussion. The researchers don't cognizant of why some with concussion history develop memory problems and others do not. The inspection was funded by the US National Institutes of Health, among several other supporters.

The go into adds valuable information for experts in the field, said Dr Robert Glatter, governor of sports medicine and traumatic brain injury in the department of emergency medicine at Lenox Hill Hospital, in New York City. Glatter, who is also a ex- sideline physician for the National Football League's New York Jets, reviewed the redesigned study findings. Other studies, he said, often rely on postmortem information.

In the Mayo study, participants had to have diminution of consciousness as a method of having a concussion history, Glatter noted. However, he added, the new thinking is that failure of consciousness is not necessary to define a concussion - one can occur without that. The effect of noggin injury may be cumulative over time in the development of Alzheimer's, he said.

In the past, experts thought only mean head trauma was linked with Alzheimer's, but less severe injury may actually be relevant as well, he added. Some other element or factors yet to be discovered may be at play, Glatter said. Both Mielke and Glatter stressed that concussions don't automatically surpass to Alzheimer's. "Not all people with head trauma forth Alzheimer's vitaros. If you do hit your head, it doesn't mean you are going to develop Alzheimer's," Mielke said, although "it may enlarge your risk".